Team GrantsCurrent Grants

Amanda Driver – Retrospective cross-sectional evaluation of clinical and immunologic outcomes in lung transplant recipients between 2014 and 2022

This project focuses on evaluating a treatment protocol introduced in 2014 for lung transplant patients with immune system reactivity towards donor organs. The number of people awaiting lung transplant exceeds the number of available donor organs, and many individuals face difficulties being matched to donor organs due to immune system reactivity. Traditionally, these individuals could not receive a transplant due to the risk of complications. However, the new treatment protocol was developed to address this issue and increase transplant eligibility for more people.

The aim of this study is to compare outcomes between people who received the new protocol and those who did not. Key outcomes will include survival rates, rejection episodes, infections, development of cancer, and length of hospitalization. The team predicts that individuals who received this protocol will have similar outcomes to those who did not, thus allowing more patients to access life-saving transplants.

The involvement of patient partners will be integral to the research. These partners will help prioritize the most important aspects of the treatment protocol from the perspective of patients and contribute valuable insight into how these protocols might be improved to enhance the overall patient experience in future cases.

Principle investigator: Amanda Driver

Co-investigators: Dr. Karen Sherwood, Dr. Robert Wright, Dr. Tanveer Brar, Dr. Nilufar Partovi, Dr. James Lan, Dr. Paul Keown and Dr. Roland Nador

Patient Partners: TBD